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MK 677 (Ibutamoren) | Encapsulated Reagent | CAS 159752-10-0 | Profound Aminos

TECHNICAL SPECIFICATIONS

• Product Name : MK 677 (Ibutamoren) Encapsulated Reagent
• Chemical Class : Spiropiperidine (Non-Peptide Secretagogue)
• CAS Number : 159752-10-0 (Mesylate Salt)
• Molecular Formula : C₂₇H₃₆N₄O₅S (Mesylate)
• Molecular Weight : 624.77 g/mol (Salt Form)
• Concentration : Standardized Molar Aliquot (High/Low Mass)
• Format : Encapsulated Powder (Open for Reconstitution)
• Variance : ±2% Gravimetric Tolerance
• Solubility : Soluble in DMSO, Ethanol, Deionized Water

Disclaimer : For Research Use Only (RUO). Not for human use.

Product Overview

This product consists of MK 677 (Ibutamoren Mesylate) encapsulated in an inert carrier for precise Laboratory Aliquoting. Unlike traditional peptides that require complex weighing, this Non-Peptide Ghrelin Mimetic is provided in pre-measured units strictly for Solvent Solubility & Chemical Analysis, eliminating the need for milligram scales.

This format eliminates the need for analytical balances in high-throughput environments.

Chemical Diagram

Chemical Structure of MK 677

2D Chemical Structure of MK 677 (Ibutamoren Mesylate) – Research Grade Spiropiperidine Ligand

Molecular Specification. The verified 2D diagram of Ibutamoren Mesylate (C₂₇H₃₆N₄O₅S).
Note the spiro-piperidine scaffold, which grants oral bioavailability and high affinity for the GHSR1a receptor in metabolic assays.

Regulatory Status : Research Use Only (RUO). Not for human consumption, diagnostic, or clinical use.

Comparative Research Context :

Growth Hormone Axis Modulators (2026 Comparison)

Feature	MK 677 (Ibutamoren)	IPA (Selective)	CJC-1295 (No DAC)
Format	Small Molecule (Encapsulated Reagent)	Lyophilized Peptide (Vial)	Lyophilized Peptide (Vial)
Mechanism	Ghrelin Receptor (GHSR) Agonist	Selective GHS Agonist	GHRH Analog
Half-Life	~24 Hours (Long-Acting)	~2 Hours (Short-Acting)	~30 Minutes
Key Research Area	IGF-1 Sustained Elevation	Pulse GH Release	Basal GH Modulation
Primary Effect	Mimics “Hunger” Signal (Ghrelin)	No Cortisol/Prolactin Spike	Amplifies Natural Pulses

Why Researchers source from PROFOUND AMINOS

1- Pre-Weighed Precision (Gravimetric Accuracy) :

Handling loose hygroscopic powders leads to “micro-dusting” and variance in stock solution concentration. Our Encapsulated Aliquots provide a Standardized Mass (±2% Tolerance) of active reagent per unit, ensuring exact molarity when dissolved in solvent, eliminating the need for delicate weighing scales.

2 – Batch Quality Transparency (Real Data vs. Marketing) :

Most suppliers display a single, static “99% Purity” COA, hiding the reality of chemical synthesis variance. Recent 2025-2026 Chromatographic Audits of the online research market reveal that a significant percentage of generic compounds contain unlisted fillers or incorrect Active Content Mass. At Profound Aminos, we publish complete batch history showing actual purity results (e.g., 98.2% to 99.4%) across our last 12 batches. We don’t cherry-pick; we strictly document the Stoichiometric Variance, allowing researchers to calculate exact molarity for their experiments, precision that standard “flat-claim” vendors cannot guarantee.

Our Standard :

We publish Complete Batch Genealogy. Real synthesis fluctuates; our recent lots range from 98.2% to 99.4% (HPLC Verified). We reject “Flat 99.0%” claims as statistically suspicious. By providing the exact purity per batch (e.g., Batch #MK2402: 99.1%), we allow researchers to calculate the actual active milligrams for their experiments, ensuring reproducibility that generic vendors cannot match.

4 – Verified Mesylate Salt :

We exclusively use Ibutamoren Mesylate, the most bioavailable and stable salt form used in 90% of peer-reviewed literature. We do not use the cheaper “Free Base,” which has poor solubility in research solvents.

REGULATORY & COMPLIANCE STATEMENT

MK 677 (Ibutamoren) is classified as a Novel Chemical Entity (NCE) and is NOT a pharmaceutical agent. It is supplied strictly as a Chemical Reference Material for Research Use Only (RUO) and has not been evaluated by regulatory bodies.

Researchers must reference CAS 159752-10-0 safety protocols, as preliminary data suggests potential Systemic Reactivity and Uncharacterized Cellular Modulation in biological models.

Usage Restriction : Strictly for In-Vitro and Non-Clinical research. Any intent to use for human consumption (bodybuilding, anti-aging) will result in the immediate cancellation of your order and blacklisting from our platform.

Frequently Asked Questions

Q1: Is MK 677 a SARM?

A: Technically, NO. MK 677 is classified as a Non-Peptide Ghrelin Mimetic. It selectively targets the GHSR1a receptor (Ghrelin pathway) and does not interact with Androgen Receptors. It is frequently categorized alongside SARMs in catalogs simply due to comparable oral bioavailability profiles in research settings.

Q2: Is this product intended for oral administration?

A: NO. This format is a Pre-Weighed Reagent Aliquot designed solely to ensure precise dosing for solvent dissolution. The outer shell acts as a carrier and must be opened or dissolved in reagent-grade solvent (e.g., DMSO/Water) for In-Vitro application. It is not for human or animal consumption.

Q3: What solvents dissolve the capsule content?

A: The active ingredient (Ibutamoren Mesylate) is water-soluble. However, for cellular assays, we recommend opening the carrier and dissolving the powder in DMSO or Deionized Water to create a stock solution.

Q4: Does this ligand display off-target binding variance?

A: High Selectivity Profile. Structural binding assays confirm that Ibutamoren is highly selective for the GHSR1a (Ghrelin) Receptor. It displays negligible binding affinity for Tyrosine Kinase or Nuclear Receptor families. Researchers utilize it to isolate specific G-Protein signaling vectors without interference from divergent metabolic pathways.

Q5: What is the shelf life of the reagent?

A: The encapsulated format protects the hygroscopic powder from moisture. Shelf life is 3 years when stored at room temperature (cool, dry place). Avoid high humidity.

Q6: How does the mechanism differ from exogenous polypeptide administration?

A: Direct introduction of synthetic polypeptides often downregulates receptor sensitivity. This Non-Peptide Ligand preserves Endogenous Signaling Cascades via the GHSR1a pathway. This distinction allows researchers to investigate Natural Feedback Loops and receptor kinetics without the suppressive effects associated with external polypeptide introduction

Q7: Is this compound banned?

A: MK 677 is banned by WADA for athletic use. However, it is Legal for Research Use in the USA (non-scheduled). It is not a controlled substance, but it is strictly an unapproved chemical for lab use.

Q8: Can this be used for “cutting” research?

A: No. While it alters metabolic rate, MK 677 is a Ghrelin mimetic, which significantly increases appetite signaling. It is typically studied for Nitrogen Retention (Anabolic State) rather than deficit models.

Q9: What is the purity of your MK 677?

A: We guarantee ≥99% Purity via HPLC analysis. As mentioned in our transparency policy, exact batch purity (e.g., 99.1% vs 99.4%) is documented on the COA provided with every order.

Q10: Why does the powder clump inside the carrier?

A: Ibutamoren Mesylate is hygroscopic (attracts water molecules). Slight clumping is a normal physical property of the salt and does not affect chemical stability or potency.

Strength	20mg
Count	60 Capsules

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DISCLAIMER:

• Products sold on our website are meant for scientific research purposes only, designed for in vitro testing and lab experimentation exclusively. These products are not intended to be used as foods, drugs or cosmetics, any sort of bodily introduction of the products into humans or animals is strictly prohibited. They must also not be misbranded, misused, or mislabeled, or used for anything other than research and scientific investigation.
• All the products you see on the website are being sold in a lyophilized powder state (freeze-dried), in a sealed sterile vial; and should be reconstituted.
  The product’s label clearly states the amount of product a vial contains; some products are offered in different variations.
• The products we are selling come in a sealed vial but require additional lab equipment for proper testing. 
• Though we make sure packaging, label, seals and writing does not differ from the product photos you see on our website, there is a chance for a minimal deviation.